Article
DNA sequence polymorphisms in a panel of eight candidate bovine imprinted genes and their association with performance traits in Irish Holstein-Friesian cattle.
BMC genetics - 13 Oct 2010
Magee David A, Sikora Klaudia M, Berkowicz Erik W, Berry Donagh P, Howard Dawn J, Mullen Michael P, Evans Ross D, Spillane Charles, MacHugh David E
Abstract excerpt
BACKGROUND: Studies in mice and humans have shown that imprinted genes, whereby expression from one of the two parentally inherited alleles is attenuated or completely silenced, have a major effect on mammalian growth, metabolism and physiology. More recently, investigations in livestock species indicate that genes subject to this type of epigenetic regulation contribute to, or are associated with, several...
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