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Article

Functional confirmation of PLAG1 as the candidate causative gene underlying major pleiotropic effects on body weight and milk characteristics.

Scientific reports - 21 Mar 2017

Fink Tania, Tiplady Kathryn, Lopdell Thomas, Johnson Thomas, Snell Russell G, Spelman Richard J, Davis Stephen R, Littlejohn Mathew D

Abstract excerpt

A major pleiotropic quantitative trait locus (QTL) located at ~25 Mbp on bovine chromosome 14 affects a myriad of growth and developmental traits in Bos taurus and indicus breeds. These QTL have been attributed to two functional variants in the bidirectional promoter of PLAG1 and CHCHD7. Although...

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Share to Body Weight
Share to Cattle
Share to Chromosomes, Mammalian

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dairying

Share to Genetic Pleiotropy

Share to Quantitative Trait, Heritable

Share to Reproducibility of Results

Source

Open in PubMed Open full text

Identifiers

PMID: 28322319
DOI: 10.1038/srep44793
PMCID: PMC5359603

Genes

PLAG1
CHCHD7
LYN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-28322319-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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