Article
[Transmission disequilibrium test for 15 short tandem repeat loci in Kashin-Beck disease and their interaction with low selenium].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University - 1 Apr 2011
Shi Xiao-Wei, Lv Ai-Li, Ren Feng-Ling, Li Wen-Rong, Kang Long-Li, Guo Xiong
Abstract excerpt
OBJECTIVE: To identify the genetic susceptibility to Kashin-Beck disease (KBD) and explore the interaction between low selenium (Se) and the susceptibility gene loci in KBD. METHODS: The DNA samples collected from 23 KBD nuclear families were analyzed using PCR and GeneScan Analysis 3.7 and Genotyper3.7 software. The haplotype relative risk (HRR) and transmission disequilibrium test (TDT) were used to test the...
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