Article
Amerindian mtDNA haplogroups and celiac disease risk HLA haplotypes in mixed-blood Latin American patients.
Journal of pediatric gastroenterology and nutrition - 1 Oct 2011
Parada Alejandra, Araya Magdalena, Pérez-Bravo Francisco, Méndez Marco, Mimbacas Adriana, Motta Patricia, Martín Graciela, Martín Gabriela, Botero Jorge, Espinosa Nelly, Alarcon Teresa, Canales Paulina
Abstract excerpt
BACKGROUND AND OBJECTIVE: Risk haplotypes have been described in celiac disease (CD), but the influence of native genes on CD in Hispanic Americans is unknown. The aim of the study was to measure the frequency of Amerindian mitochondrial DNA (mtDNA) haplogroups (inherited by the maternal line) in mixed-blood patients with CD from Chile, Argentina, and Uruguay, and to assess the relation between these and human...
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