Article
Mixtec Mexican Amerindians: an HLA alleles study for America peopling, pharmacogenomics and transplantation.
Immunological investigations - 1 Jan 2014
Arnaiz-Villena Antonio, Vargas-Alarcón Gilberto, Areces Cristina, Enríquez-de-Salamanca Mercedes, Abd-El-Fatah-Khalil Sedeka, Fernández-Honrado Mercedes, Marco Javier, Martín-Villa José Manuel, Rey Diego
Abstract excerpt
HLA-A, -B and -DRB1 alleles have been studied in a Mixtec Mexican Amerindian population by indirect DNA sequencing. HLA relatedness has been tested by comparing results with other Amerindians and worldwide populations; a total of 15,681 chromosomes have been used. Genetic distances between populations, Neighbour Joining (NJ) dendrograms and correspondence analyses have been carried out. Conclusions are: 1) Our...
Topics
- Alleles
- Ethnicity
- HLA-A Antigens
- HLA-B Antigens
- HLA-DRB1 Chains
- Histocompatibility Testing
- Humans
- Mexico
- Organ Transplantation
- Pharmacogenetics