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Article

DNA Aptamers Binding to Multiple Prevalent M-Types of <i>Streptococcus pyogenes</i>

19 Apr 2011

Abstract excerpt

This paper describes the selection of high affinity DNA aptamers binding to multiple M-types of the pathogenic species Streptococcus pyogenes (Group A Streptococcus or GAS). Unlike common aptamer selection techniques that use purified molecules of a monoclonal cell population as targets, this work has achieved the selection of aptamers against the various M-types of S. pyogenes. Cell mixtures containing equal...

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Share to Advanced biosensing and bioanalysis techniques
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PMID: 21504182
DOI: 10.1021/ac200575e

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