microRNAs in Early Diabetic Retinopathy in Streptozotocin-Induced Diabetic Rats

Abstract excerpt

PURPOSE: Diabetic retinopathy (DR) is one of the leading causes of blindness. However, the roles of microRNAs (miRNAs) in DR are still unknown. The aims of this study were to identify miRNAs involved in early DR and to characterize their roles in the pathogenesis of DR. METHODS: miRNA-expression profiling was performed in the retina and retinal endothelial cells (RECs) of streptozotocin (STZ)-induced diabetic...

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