Article
Coronary artery endothelial transcriptome in vivo: identification of endoplasmic reticulum stress and enhanced reactive oxygen species by gene connectivity network analysis.
Circulation. Cardiovascular genetics - 1 Jun 2011
Civelek Mete, Manduchi Elisabetta, Riley Rebecca J, Stoeckert Christian J, Davies Peter F
Abstract excerpt
BACKGROUND: Endothelial function is central to the localization of atherosclerosis. The in vivo endothelial phenotypic footprints of arterial bed identity and site-specific atherosusceptibility are addressed. METHODS AND RESULTS: Ninety-eight endothelial cell samples from 13 discrete coronary and noncoronary arterial regions of varying susceptibilities to atherosclerosis were isolated from 76 normal swine....
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