Article
Single nucleotide polymorphisms at the TRAF1/C5 locus are associated with rheumatoid arthritis in a Han Chinese population.
BMC medical genetics - 14 Apr 2011
Zhu Jing, Zhang Dinging, Wu Fengxia, He Fei, Liu Xiaoqi, Wu Lijun, Zhou Bin, Liu Jianping, Lu Fang, Liu Jian, Luo Ruijun, Long Wubin, Yang Minghui, Ma Shi, Wu Xiaodan, Shi Yi, Wu Tong, Lin Ying, Yang Jiyun, Yuan Guohua, Yang Zhenglin
Abstract excerpt
BACKGROUND: Genetic variants in TRAF1C5 and PTPN22 genes have been shown to be significantly associated with arthritis rheumatoid in Caucasian populations. This study investigated the association between single nucleotide polymorphisms (SNPs) in TRAF1/C5 and PTPN22 genes and rheumatoid arthritis (RA) in a Han Chinese population. We genotyped SNPs rs3761847 and rs7021206 at the TRAF1/C5 locus and rs2476601 SNP in...
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