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Article

Flexible estimation of covariance function by penalized spline with application to longitudinal family data.

Statistics in medicine - 10 Jul 2011

Wang Yuanjia

Abstract excerpt

Longitudinal data are routinely collected in biomedical research studies. A natural model describing longitudinal data decomposes an individual's outcome as the sum of a population mean function and random subject-specific deviations. When parametric assumptions are too restrictive, methods modeling the population mean function and the random subject-specific functions nonparametrically are in demand. In some...

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PMID: 21491474
DOI: 10.1002/sim.4236
PMCID: PMC3115522

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