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Article

New attenuated vaccine against columnaris disease in fish: choosing the right parental strain is critical for vaccine efficacy.

Vaccine - 25 Oct 2013

Mohammed Haitham, Olivares-Fuster Oscar, LaFrentz Stacey, Arias Covadonga R

Abstract excerpt

Flavobacterium columnare, the causative agent of columnaris disease, is a highly diverse species comprised by three genomovars. Genomovar II strains are more virulent toward catfishes than genomovar I isolates. The objective of this study was to compare the vaccine efficacy of avirulent mutants derived from genomovars I and II using a rifampicin-resistance strategy. First, we compared the efficacy of 13 genomovar...

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Source

Identifiers

PMID: 24012568
DOI: 10.1016/j.vaccine.2013.08.052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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