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Article

Polymorphisms in the endothelin-1 and endothelin a receptor genes and survival in patients with locoregionally advanced nasopharyngeal carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Apr 2011

Wen Yue-Feng, Qi Bin, Liu Huai, Mo Hao-Yuan, Chen Qiu-Yan, Li Juan, Huang Pei-Yu, Ye Yan-Fang, Zhang Ying, Deng Man-Quan, Guo Xiang, Hong Ming-Huang, Cao Ka-Jia, Mai Hai-Qiang

Abstract excerpt

PURPOSE: We aimed to investigate the prognostic role of endothelin-1 (EDN1) and endothelin A receptor (EDNRA) gene polymorphisms in patients with locoregionally advanced nasopharyngeal carcinoma (NPC). EXPERIMENTAL DESIGN: Two hundred three consecutive patients with locoregionally advanced NPC were enrolled. Seven potentially functional polymorphisms in the EDN1 and EDNRA genes were determined by ligase detection...

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Source

Identifiers

PMID: 21487064
DOI: 10.1158/1078-0432.CCR-10-2264

Genes

EDNRA
EDN1

Variants

Provenance

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