Article
Cloning, expression, and mutation analysis of NOR1, a novel human gene down-regulated in HNE1 nasopharyngeal carcinoma cell line.
Journal of cancer research and clinical oncology - 1 Jul 2003
Nie Xinmin, Zhang Bicheng, Li Xiaoling, Xiang Juanjuan, Xiao Bingyi, Ma Jian, Zhou Ming, Zhu Shiguo, Lu Hongbin, Gui Rong, Shen Shourong, Li Guiyuan
Abstract excerpt
PURPOSE: To investigate cloning, expression, and mutation analysis of the putative candidate tumor suppressor gene related with nasopharyngeal carcinoma (NPC). METHODS: We studied the expression profiles in the NPC cell line HNE(1) with the normal nasopharyngeal epithelial cell as control by using cDNA array representing 11,000 cDNA clusters. EST W95442 was found down-regulated in HNE(1). Subsequently, the...
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