Article
Radiolabeling and in vivo imaging of transplanted renal lineages differentiated from human embryonic stem cells in fetal rhesus monkeys.
Molecular imaging and biology - 1 Apr 2012
Tarantal Alice F, Lee C Chang I, Batchelder Cynthia A, Christensen Jared E, Prater Daniel, Cherry Simon R
Abstract excerpt
PURPOSE: The goals of this study were to optimize radiolabeling of renal lineages differentiated from human embryonic stem (hES) cells and use noninvasive imaging (positron emission tomography (PET) and bioluminescence imaging (BLI)) to detect the cells in fetal monkeys post-transplant. PROCEDURES: hES cells expressing firefly luciferase (5 × 10(6)) were radiolabeled with the optimized concentration of 10 μCi/ml...
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