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Thyroid Hormone Signaling in the Xenopus laevis Embryo Is Functional and Susceptible to Endocrine Disruption

12 Sept 2012

Abstract excerpt

Thyroid hormone (TH) is essential for vertebrate brain development. Most research on TH and neuronal development focuses on late development, mainly the perinatal period in mammals. However, in human infants neuromotor development correlates best with maternal TH levels in the first trimester of pregnancy, suggesting that TH signaling could affect early brain development. Studying TH signaling in early...

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PMID: 22968643
DOI: 10.1210/en.2012-1463

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