Article
Functional divergence among silkworm antimicrobial peptide paralogs by the activities of recombinant proteins and the induced expression profiles.
PloS one - 29 Mar 2011
Yang Wanying, Cheng Tingcai, Ye Mingqiang, Deng Xiaojuan, Yi Huiyu, Huang Yadong, Tan Xiang, Han Dong, Wang Bo, Xiang Zhonghuai, Cao Yang, Xia Qingyou
Abstract excerpt
Antimicrobial peptides are small-molecule proteins that are usually encoded by multiple-gene families. They play crucial roles in the innate immune response, but reports on the functional divergence of antimicrobial peptide gene families are rare. In this study, 14 paralogs of antimicrobial peptides belonging to cecropin, moricin and gloverin families were recombinantly expressed in pET expression systems. By...
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