Article
MicroRNA misregulation: an overlooked factor generating somaclonal variation?
Trends in plant science - 1 May 2011
Rodriguez-Enriquez J, Dickinson H G, Grant-Downton R T
Abstract excerpt
Somaclonal variation is an important phenomenon that can be observed at high levels in plant tissue culture. Although known to science since plant cell culture techniques were first developed, its origins remain mysterious. Here, we propose that misregulation of microRNAs and small RNA pathways can make a significant contribution to the phenomenon. For many reasons, microRNAs and related small RNAs appear ideal...
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