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Article

Carboplatin plus pemetrexed for platinum-pretreated, advanced non-small cell lung cancer: a retrospective study with pharmacogenetic evaluation.

Cancer chemotherapy and pharmacology - 1 Dec 2011

Metro Giulio, Chiari R, Mare M, Giannarelli D, Tofanetti F R, Minotti V, Ferraldeschi M, Giuffrida D, Marcomigni L, Bennati C, Fischer M J, Meacci M, Bellavita R, Pistola L, Ludovini V, Crinò L

Abstract excerpt

PURPOSE: In the present study, the combination of carboplatin (CBDCA) plus pemetrexed (PMX) for the treatment of patients with platinum-pretreated, pemetrexed-naïve, advanced non-small cell lung cancer (NSCLC) was investigated. Also, single nucleotide polymorphisms (SNPs) at the XRCC3, XPD, ERCC1, GARFT, DHFR, and TS genes were investigated. METHODS: Eighty patients treated with CBDCA/PMX at two Italian...

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Identifiers

PMID: 21468755
DOI: 10.1007/s00280-011-1632-x

Genes

DHFR
ERCC1
XRCC3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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