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Article

Protection against divergent influenza H1N1 virus by a centralized influenza hemagglutinin.

PloS one - 28 Mar 2011

Weaver Eric A, Rubrum Adam M, Webby Richard J, Barry Michael A

Abstract excerpt

Influenza poses a persistent worldwide threat to the human population. As evidenced by the 2009 H1N1 pandemic, current vaccine technologies are unable to respond rapidly to this constantly diverging pathogen. We tested the utility of adenovirus (Ad) vaccines expressing centralized consensus influenza antigens. Ad vaccines were produced within 2 months and protected against influenza in mice within 3 days of...

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Share to Adenoviridae
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Share to Hemagglutinin Glycoproteins, Influenza Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunity, Cellular

Share to Immunity, Humoral

Share to Influenza A Virus, H1N1 Subtype

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Source

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Identifiers

PMID: 21464940
DOI: 10.1371/journal.pone.0018314
PMCID: PMC3065472

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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