Article
Transmitted resistance to HIV integrase strand-transfer inhibitors: right on schedule.
Antiviral therapy - 1 Jan 2011
Hurt Christopher B
Abstract excerpt
Transmitted drug resistance (TDR), the primary acquisition of an HIV variant already resistant to antiretrovirals, affects approximately 15% of all new infections in the United States. Historically, from the time initial agents in the reverse transcriptase, protease and entry inhibitor classes were introduced, it took 3-5 years before the first case reports of TDR appeared. With the description of the first two...
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