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Article

Serotonin transporter gene polymorphism implicates reduced orbito-frontal cortex in obsessive-compulsive disorder.

Journal of anxiety disorders - 1 Jun 2011

Atmaca Murad, Onalan Ebru, Yildirim Hanefi, Yuce Huseyin, Koc Mustafa, Korkmaz Sevda, Mermi Osman

Abstract excerpt

Although a number of magnetic resonance imaging (MRI) and genetic studies have been performed on obsessive-compulsive disorder (OCD), only limited studies in which genetic and neuroanatomical variables are evaluated concurrently have been performed. Therefore, the aim of our present study is (to understand) better understanding how genetic variation in the promoter region of the 5-HTT gene (5-HTTLPR) is...

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Source

Identifiers

PMID: 21441009
DOI: 10.1016/j.janxdis.2011.03.002

Genes

HTT

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