Article
Absence of association between specific common variants of the obesity-related FTO gene and psychological and behavioral eating disorder phenotypes.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jun 2011
Jonassaint Charles R, Szatkiewicz Jin Peng, Bulik Cynthia M, Thornton Laura M, Bloss Cinnamon, Berrettini Wade H, Kaye Walter H, Bergen Andrew W, Magistretti Pierre, Strober Michael, Keel Pamela K, Brandt Harry, Crawford Steve, Crow Scott, Fichter Manfred M, Goldman David, Halmi Katherine A, Johnson Craig, Kaplan Allan S, Klump Kelly L, La Via Maria, Mitchell James E, Rotondo Alessandro, Treasure Janet, Woodside D Blake
Abstract excerpt
Extensive population-based genome-wide association studies have identified an association between the FTO gene and BMI; however, the mechanism of action is still unknown. To determine whether FTO may influence weight regulation through psychological and behavioral factors, seven single-nucleotide polymorphisms (SNPs) of the FTO gene were genotyped in 1,085 individuals with anorexia nervosa (AN) and 677 healthy...
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