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Article

Fat mass and obesity-associated gene (FTO) is associated to eating disorders susceptibility and moderates the expression of psychopathological traits.

PloS one - 1 Jan 2017

Castellini Giovanni, Franzago Marica, Bagnoli Silvia, Lelli Lorenzo, Balsamo Michela, Mancini Milena, Nacmias Benedetta, Ricca Valdo, Sorbi Sandro, Antonucci Ivana, Stuppia Liborio, Stanghellini Giovanni

Abstract excerpt

Eating Disorders (EDs) show a multifactorial etiopathogenesis including environmental, psychological and biological factors. In the present study, we propose a model of interactions between genetic vulnerability-represented by Fat Mass and Obesity-Associated (FTO) gene-and stable psychopathological traits, such as bodily disorders and emotion dysregulation for EDs patients. The distribution of a polymorphism of...

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Source

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Identifiers

PMID: 28282466
DOI: 10.1371/journal.pone.0173560
PMCID: PMC5345831

Genes

FTO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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