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Article

Brain-derived neurotrophic factor gene Val66Met polymorphism modulates reversible cerebral vasoconstriction syndromes.

PloS one - 18 Mar 2011

Chen Shih-Pin, Fuh Jong-Ling, Wang Shuu-Jiun, Tsai Shih-Jen, Hong Chen-Jee, Yang Albert C

Abstract excerpt

BACKGROUND: Reversible cerebral vasoconstriction syndrome (RCVS) could be complicated by cerebral ischemic events. Hypothetical mechanisms of RCVS involve endothelial dysfunction and sympathetic overactivity, both of which were reported to be related to brain-derived neurotrophic factor (BDNF). The study investigated the association between functional BDNF Val66Met polymorphism and RCVS. METHODS: Patients with...

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Identifiers

PMID: 21437208
DOI: 10.1371/journal.pone.0018024
PMCID: PMC3060928

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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