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Article

A Perspective on Cancer Cell Metastasis

24 Mar 2011

Abstract excerpt

Metastasis causes most cancer deaths, yet this process remains one of the most enigmatic aspects of the disease. Building on new mechanistic insights emerging from recent research, we offer our perspective on the metastatic process and reflect on possible paths of future exploration. We suggest that metastasis can be portrayed as a two-phase process: The first phase involves the physical translocation of a cancer...

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PMID: 21436443
DOI: 10.1126/science.1203543

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