Article
Preliminary evidence that allelic variation in the LMX1A gene influences training-related working memory improvement.
Neuropsychologia - 1 Jun 2011
Bellander Martin, Brehmer Yvonne, Westerberg Helena, Karlsson Sari, Fürth Daniel, Bergman Olle, Eriksson Elias, Bäckman Lars
Abstract excerpt
LMX1A is a transcription factor involved in the development of dopamine (DA)-producing neurons in midbrain. Previous research has shown that allelic variations in three LMX1A single nucleotide polymorphisms (SNPs) were related to risk of Parkinson's disease (PD), suggesting that these SNPs may influence the number of mesencephalic DA neurons. Prompted by the established link between striatal DA functions and...
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