Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Correlation of SHOX2 Gene Amplification and DNA Methylation in Lung Cancer Tumors

22 Mar 2011

Abstract excerpt

BACKGROUND: DNA methylation in the SHOX2 locus was previously used to reliably detect lung cancer in a group of critical controls, including 'cytologically negative' samples with no visible tumor cell content, at a high specificity based on the analysis of bronchial lavage samples. This study aimed to investigate, if the methylation correlates with SHOX2 gene expression and/or copy number alterations. An...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genomic variations and chromosomal abnormalities
Share to Lung Cancer Treatments and Mutations
Share to Microtubule and mitosis dynamics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21426551
DOI: 10.1186/1471-2407-11-102

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Correlation of SHOX2 Gene Amplification and DNA Methylation in Lung Cancer TumorsPMID 21426551Read ↗

The value of SHOX2 methylation test in peripheral blood samples used for the differential diagnosis of lung cancer and other lung disordersSemantic proximity Read ↗

A systematic review and meta analysis of the valve of SHOX2 and RASSF1A gene methylation in bronchial elveslar lavage fluid in the diagnosis of lung cancerSemantic proximity Read ↗

SHOX2 methylation in Vietnamese patients with lung cancerSemantic proximity Read ↗

Diagnostic performance of SHOX2 promoter methylation as biomarker for lung cancer identification: A meta‐analysis updateSemantic proximity Read ↗

DNA methylation analysis in plasma for early diagnosis in lung adenocarcinomaSemantic proximity Read ↗

The Combination of SHOX2 and RASSF1A DNA Methylation Had a Diagnostic Value in Pulmonary Nodules and Early Lung CancerSemantic proximity Read ↗

Diagnostic performance of RASSF1A and SHOX2 methylation combined with EGFR mutations for differentiation between small pulmonary nodules.Semantic proximity Read ↗

DNA methylation analysis of tumor suppressor genes in liquid biopsy components of early stage NSCLC: a promising tool for early detectionSemantic proximity Read ↗

Combined Methylation of SHOX2 and RASSF1A Genes in Diagnosing Malignant Pleural EffusionSemantic proximity Read ↗

Quantification of cell-free mSHOX2 Plasma DNA for therapy monitoring in advanced stage non-small cell (NSCLC) and small-cell lung cancer (SCLC) patients.Semantic proximity Read ↗

DNA Methylation Analysis of the SHOX2 and RASSF1A Panel Using Cell-Free DNA in the Diagnosis of Malignant Pleural EffusionSemantic proximity Read ↗

Validation of the SHOX2 / PTGER4 DNA Methylation Marker Panel for Plasma-Based Discrimination between Patients with Malignant and Nonmalignant Lung DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.