Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Diagnostic performance of RASSF1A and SHOX2 methylation combined with EGFR mutations for differentiation between small pulmonary nodules.

Journal of cancer research and clinical oncology - 1 Sept 2023

Ji Xiang-Yu, Li Hong, Chen Hui-Hui, Lin Jie

Abstract excerpt

BACKGROUND AND AIM: Aberrant methylation of Ras association domain family 1, isoform A (RASSF1A), and short-stature homeobox gene 2 (SHOX2) promoters has been validated as a pair of valuable biomarkers for diagnosing early lung adenocarcinomas (LUADs). Epidermal growth factor receptor (EGFR) is the key driver mutation in lung carcinogenesis. This study aimed to investigate the aberrant promoter methylation of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma of Lung
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to ErbB Receptors

Share to Homeodomain Proteins

Share to Lung Neoplasms

Share to Mutation

Source

Identifiers

PMID: 37097393
DOI: 10.1007/s00432-023-04745-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Diagnostic performance of RASSF1A and SHOX2 methylation combined with EGFR mutations for differentiation between small pulmonary nodules.PMID 37097393Read ↗

DNA methylation analysis in plasma for early diagnosis in lung adenocarcinomaSemantic proximity Read ↗

The Combination of SHOX2 and RASSF1A DNA Methylation Had a Diagnostic Value in Pulmonary Nodules and Early Lung CancerSemantic proximity Read ↗

Diagnostic performance of SHOX2 promoter methylation as biomarker for lung cancer identification: A meta‐analysis updateSemantic proximity Read ↗

Combined Methylation of SHOX2 and RASSF1A Genes in Diagnosing Malignant Pleural EffusionSemantic proximity Read ↗

A Panel of DNA Methylation Biomarkers for Detection and Improving Diagnostic Efficiency of Lung CancerSemantic proximity Read ↗

A novel multimodal prediction model based on DNA methylation biomarkers and low-dose computed tomography images for identifying early-stage lung cancerSemantic proximity Read ↗

A systematic review and meta analysis of the valve of SHOX2 and RASSF1A gene methylation in bronchial elveslar lavage fluid in the diagnosis of lung cancerSemantic proximity Read ↗

The value of SHOX2 methylation test in peripheral blood samples used for the differential diagnosis of lung cancer and other lung disordersSemantic proximity Read ↗

DNA Methylation Analysis of the SHOX2 and RASSF1A Panel Using Cell-Free DNA in the Diagnosis of Malignant Pleural EffusionSemantic proximity Read ↗

Detection of the DNA methylation of seven genes contribute to the early diagnosis of lung cancerSemantic proximity Read ↗

A combined model of circulating tumor DNA methylated SHOX2/SCT/HOXA7 and clinical features facilitates the discrimination of malignant from benign pulmonary nodulesSemantic proximity Read ↗

DNA methylation analysis of tumor suppressor genes in liquid biopsy components of early stage NSCLC: a promising tool for early detectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.