Article
Membrane association and secretion of the Japanese encephalitis virus NS1 protein from cells expressing NS1 cDNA.
Virology - 1 Aug 1990
Fan W F, Mason P W
Abstract excerpt
The biosynthesis of the flavivirus nonstructural glycoprotein, NS1, has important implications for (1) vaccine production, since NS1 immunity can protect animals from flavivirus infection; and (2) virion maturation, since NS1 is coretained with immature forms of the structural glycoprotein E in the endoplasmic reticulum (ER) of infected cells. To examine the molecular basis for NS1 retention within the ER we have...
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