Article
Requirement of the N-terminal region of orthobunyavirus nonstructural protein NSm for virus assembly and morphogenesis.
Journal of virology - 1 Aug 2006
Shi Xiaohong, Kohl Alain, Léonard Vincent H J, Li Ping, McLees Angela, Elliott Richard M
Abstract excerpt
The nonstructural protein NSm of Bunyamwera virus (BUNV), the prototype of the Bunyaviridae family, is encoded by the M segment in a polyprotein precursor, along with the virion glycoproteins, in the order Gn-NSm-Gc. As little is known of its function, we examined the intracellular localization, membrane integrality, and topology of NSm and its role in virus replication. We confirmed that NSm is an integral...
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