Article
Analysis of sequence variations in low-density lipoprotein receptor gene among Malaysian patients with familial hypercholesterolemia.
BMC medical genetics - 19 Mar 2011
Al-Khateeb Alyaa, Zahri Mohd K, Mohamed Mohd S, Sasongko Teguh H, Ibrahim Suhairi, Yusof Zurkurnai, Zilfalil Bin A
Abstract excerpt
BACKGROUND: Familial hypercholesterolemia is a genetic disorder mainly caused by defects in the low-density lipoprotein receptor gene. Few and limited analyses of familial hypercholesterolemia have been performed in Malaysia, and the underlying mutations therefore remain largely unknown.We studied a group of 154 unrelated FH patients from a northern area of Malaysia (Kelantan). The promoter region and exons 2-15...
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