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Article

Geometric Control of Cardiomyogenic Induction in Human Pluripotent Stem Cells

18 Mar 2011

Abstract excerpt

Although it has been observed that aggregate size affects cardiac development, an incomplete understanding of the cellular mechanisms underlying human pluripotent stem cell-derived cardiomyogenesis has limited the development of robust defined-condition cardiac cell generation protocols. Our objective was thus to elucidate cellular and molecular mechanisms underlying the endogenous control of human embryonic stem...

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PMID: 21417693
DOI: 10.1089/ten.tea.2010.0563

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