Article
Proliferation of smooth muscle cells stimulated by Porphyromonas gingivalis is inhibited by apple polyphenol.
Journal of periodontology - 1 Nov 2011
Inaba Hiroaki, Tagashira Motoyuki, Kanda Tomomasa, Amano Atsuo
Abstract excerpt
BACKGROUND: Porphyromonas gingivalis (Pg) is thought to be involved in the progression of occlusive arterial lesions, whereas vascular smooth muscle cell (SMC) proliferation is considered to be involved in occlusive arterial disease. We previously showed that bacteremia caused by Pg infection induced proliferation of mouse aortic SMCs. Furthermore, human SMCs stimulated with human plasma incubated with Pg showed...
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