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Article

Epigenetic markers for chemosensitivity and chemoresistance in pancreatic cancer—A review

16 Mar 2011

Abstract excerpt

Adjuvant first-line gemcitabine monochemotherapy presents a standard treatment for patients with advanced pancreatic adenocarcinoma and improves overall survival in chemosensitive patients. Nonetheless, 6-month progression-free survival remains below 15%, despite interdisciplinary approaches. The success of gemcitabine treatment is disappointing and-in the absence of reliable tumor markers--challenging to...

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Share to Epigenetics and DNA Methylation
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PMID: 21413017
DOI: 10.1002/ijc.26078

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