Article
Susceptibility of HIV-1 subtypes B', CRF07_BC and CRF01_AE that are predominantly circulating in China to HIV-1 entry inhibitors.
PloS one - 11 Mar 2011
Yu Xiaoling, Yuan Lin, Huang Yang, Xu Weisi, Fang Zhiming, Liu Shuwen, Shao Yiming, Jiang Shibo, Ma Liying
Abstract excerpt
BACKGROUND: The B', CRF07_BC and CRF01_AE are the predominant HIV-1 subtypes in China. It is essential to determine their baseline susceptibility to HIV entry inhibitors before these drugs are used in China. METHODOLOGY/PRINCIPAL FINDINGS: The baseline susceptibility of 14 representative HIV-1 isolates (5 CRF07_BC, 4 CRF01_AE, and 5 B'), most of which were R5 viruses, obtained from drug-naïve patients to HIV...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.