Article
Analysis of Vpr Genetic Variations between Chinese Major Circulating Recombinants CRF01_AE and CRF07_BC.
Current HIV research - 1 Jan 2020
Du Ling, Wang Lina, Yu Tong, Xin Ruolei, Meng Zhefeng
Abstract excerpt
BACKGROUND: HIV-1 CRF01_AE and CRF07_BC recombinant strains are responsible for more than 80% of new infections in China since the beginning of the 2000s. These two strains may have distinct genetic mutations, which resulted in distinct patterns of pathogenesis related to the viral gene, Vpr. OBJECTIVE: The amino acid pattern and genetic diversity of Vpr were analyzed and characterized in HIV-1 CRF01_AE and...
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