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Article

Antibody binding to neuronal surface in Sydenham chorea, but not in PANDAS or Tourette syndrome

17 Mar 2011

Abstract excerpt

OBJECTIVE: To test the hypothesis that Sydenham chorea (SC) immunoglobulin G (IgG) autoantibodies bind to specific neuronal surface proteins, whereas IgG from patients with pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection (PANDAS) or Tourette syndrome (TS) do not bind to neuronal surface proteins. METHODS: We used live differentiated SH-SY5Y cells, which have neuronal and...

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PMID: 21411742
DOI: 10.1212/wnl.0b013e3182181090

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