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Article

Immunobiologic factors predictive of clinical outcome in diffuse large-cell lymphoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Jun 1990

Slymen D J, Miller T P, Lippman S M, Spier C M, Kerrigan D P, Rybski J A, Rangel C S, Richter L C, Grogan T M

Abstract excerpt

The prognostic importance of immunobiologic factors in diffuse large-cell lymphoma (DLCL) is studied in 105 consecutive DLCL patients. Multivariate results using the Cox proportional hazards model clearly indicate that the Ki-67 index (P = .002), a marker of cell proliferation activity, and the presence or absence of human leukocyte antigen-DR (HLA-DR) (P = .007) are strong predictors of survival even in the...

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PMID: 2140855
DOI: 10.1200/JCO.1990.8.6.986

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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