Article
[Testing of G----A mutation in position 110 of a minor intron of beta-globin genes in patients with thalassemia in Azerbaijan].
Molekuliarnaia genetika, mikrobiologiia i virusologiia - 1 Jan 1990
Fedorov A N, Rasulov E M, Oretskaia T S, Lebedeva I V, Ivanovskaia M G, Shabarova Z A, Limborskaia S A
Abstract excerpt
A point mutation G-A in the 110 position of the beta-globin gene small intron has been revealed by cloning and sequencing from the material of a homozygote beta-thalassemia patient in Azerbaijan. In the present study two allele-specific oligonucleotide probes for testing the mutation have been sy...
Topics
- Azerbaijan
- Base Sequence
- Globins
- Humans
- Introns
- Molecular Sequence Data
- Mutation
- Oligonucleotide Probes
- Polymerase Chain Reaction
- Thalassemia