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Kinetic modelling of lactate utilization and butyrate production by key human colonic bacterial species

9 Mar 2011

Abstract excerpt

Butyrate is the preferred energy source for colonocytes and has an important role in gut health; in contrast, accumulation of high concentrations of lactate is detrimental to gut health. The major butyrate-producing bacterial species in the human colon belong to the Firmicutes. Eubacterium hallii and a new species, Anaerostipes coli SS2/1, members of clostridial cluster XIVa, are able to utilize lactate and...

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PMID: 21388423
DOI: 10.1111/j.1574-6941.2011.01085.x

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