Article
Novel mutations in a patient isolate of Streptococcus agalactiae with reduced penicillin susceptibility emerging after long-term oral suppressive therapy.
Antimicrobial agents and chemotherapy - 1 Jun 2011
Longtin Jean, Vermeiren Christie, Shahinas Dea, Tamber Gurdip Singh, McGeer Allison, Low Donald E, Katz Kevin, Pillai Dylan R
Abstract excerpt
Penicillin nonsusceptibility has been demonstrated in group B streptococci (GBS), but there is limited information regarding mechanisms of resistance. We report a case of GBS with reduced susceptibility to penicillin emerging after long-term suppressive oral penicillin therapy for a prosthetic joint infection. Molecular characterization of the isolate before and after long-term penicillin therapy revealed 5...
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