Article
Common variants near MC4R: exploring gender effects in overweight and obese children and adolescents participating in a lifestyle intervention.
Obesity facts - 1 Jan 2011
Vogel Carla I G, Boes Tanja, Reinehr Thomas, Roth Christian L, Scherag Susann, Scherag André, Hebebrand Johannes, Hinney Anke
Abstract excerpt
OBJECTIVE: Association with obesity and increased insulin levels have been reported for two variants (rs17782313 and rs12970134) located downstream of the melanocortin-4 receptor gene (MC4R). METHODS: We investigated whether these variants have sex-specific effects on overweight, obesity and 14 related phenotypes in 889 overweight and obese children and adolescents. We also explored the impact of the variants on...
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