Balanced complex chromosome rearrangements: Reproductive aspects. A review

doi:10.1002/ajmg.a.35220

Article

Balanced complex chromosome rearrangements: Reproductive aspects. A review

1 Mar 2012

Abstract excerpt

This review examines the reproductive consequences for carriers of a balanced complex chromosome rearrangement (CCR). It is based on an analysis of CCRs in 103 adults referred for reproductive problems, including male infertility. The main focus is on reproductive risks based on data from 84 CCRs. Carriers of balanced CCRs have a high risk of an abortion and/or a chromosomally unbalanced child. I have identified...

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