Article
Sperm FISH and chromatin integrity in spermatozoa from a t(6;10;11) carrier.
Reproduction (Cambridge, England) - 1 May 2014
Olszewska Marta, Huleyuk Nataliya, Fraczek Monika, Zastavna Danuta, Wiland Ewa, Kurpisz Maciej
Abstract excerpt
Complex chromosome rearrangements (CCRs) are structurally balanced or unbalanced aberrations involving more than two breakpoints on two or more chromosomes. CCRs can be a potential reason for genomic imbalance in gametes, which leads to a drastic reduction in fertility. In this study, the meiotic segregation pattern, aneuploidy of seven chromosomes uninvolved in the CCR and chromatin integrity were analysed in...
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