Article
Relationship between MTNR1B (melatonin receptor 1B gene) polymorphism rs10830963 and glucose levels in overweight children and adolescents.
Pediatric diabetes - 1 Jun 2011
Reinehr Thomas, Scherag André, Wang Hai-Jun, Roth Christian L, Kleber Michaela, Scherag Susann, Boes Tanja, Vogel Carla, Hebebrand Johannes, Hinney Anke
Abstract excerpt
AIMS: The G-allele of the single nucleotide polymorphism (SNP) rs10830963 in MTNR1B (melatonin receptor 1B gene) is associated with type 2 diabetes mellitus and glucose levels in adults. The aim of this study was to analyze whether there is an allele-dosage effect on glucose metabolism in overweight children and to explore if changes in glucose metabolism in a lifestyle intervention do also depend on genotype....
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