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Article

Molecular repair of a defective CFTR protein in cystic fibrosis.

Clinics and research in hepatology and gastroenterology - 1 Apr 2011

Erlinger S

Abstract excerpt

We analyse a paper, which reports an entirely novel approach to the treatment of cystic fibrosis, consisting in "repairing" the defective mutant protein. Patients with cystic fibrosis have a mutation of the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR), an epithelial chloride channel involved in salt and fluid transport in multiple organs, including the lungs and pancreas. The...

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Source

Identifiers

PMID: 21349786
DOI: 10.1016/j.clinre.2011.01.003

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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