Article
Analysis of genotypic variation in genes associated with virulence in Aggregatibacter actinomycetemcomitans clinical isolates.
Journal of periodontal research - 1 Jun 2011
Pinheiro E T, Kawamoto D, Ota-Tsuzuki C, Almeida L R S, Nunes A C R, Longo P L, Wikstrom M, Mayer M P A
Abstract excerpt
BACKGROUND AND OBJECTIVE: Although certain serotypes of Aggregatibacter actinomycetemcomitans are associated more with aggressive periodontitis than are other serotypes, the correlation between distinct lineages and virulence traits in this species is poorly understood. This study aimed to evaluate the polymorphism of genes encoding putative virulence factors of clinical isolates, and to correlate these findings...
Topics
- Actinobacillus Infections
- Adhesins, Bacterial
- Aggregatibacter actinomycetemcomitans
- Aggressive Periodontitis
- Alleles
- Bacterial Outer Membrane Proteins
- Bacterial Toxins
- Base Pairing
- Chronic Periodontitis
- DNA Fingerprinting
- Deoxyribonucleases, Type II Site-Specific
- Exotoxins