Article
Genetic diversity and toxic activity of Aggregatibacter actinomycetemcomitans isolates.
Oral microbiology and immunology - 1 Dec 2009
Kawamoto D, Ando E S, Longo P L, Nunes A C R, Wikström M, Mayer M P A
Abstract excerpt
INTRODUCTION: Very little is known of the diversity and expression of virulence factors of serotypes of Aggregatibacter actinomycetemcomitans. Toxic activity on Chinese hamster ovary (CHO) cells and cdt and ltx genotyping were evaluated in A. actinomycetemcomitans serotypes. METHODS: Forty-one A. actinomycetemcomitans isolates were analysed for CHO cell growth inhibition. Genotyping was performed by polymerase...
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