Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Senescent males carry premutagenic lesions in sperm

7 Jan 2011

Abstract excerpt

As organisms age, DNA of somatic cells deteriorates, but it is believed that germ cells are protected from DNA-damaging agents. In recent years, this vision has been challenged by studies on humans indicating that genomic instability in germ cells increases with age. However, nothing is known about germ line senescence in wild animals. Here, we examine DNA damage in sperm of a wild vertebrate, the blue-footed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Behavior and Reproduction
Share to Genetics, Aging, and Longevity in Model Organisms
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21332857
DOI: 10.1111/j.1420-9101.2010.02201.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Senescent males carry premutagenic lesions in spermPMID 21332857Read ↗

Avoiding bad genes: oxidatively damaged DNA in germ line and mate choice.Semantic proximity Read ↗

The deteriorating soma and the indispensable germline: gamete senescence and offspring fitnessSemantic proximity Read ↗

Origins and consequences of DNA damage in male germ cellsSemantic proximity Read ↗

Healthy ageing men have normal reproductive function but display germline-specific molecular changesSemantic proximity Read ↗

Low mutation rate but high male-bias in the germline of a short-lived opossumSemantic proximity Read ↗

Dear Old DadSemantic proximity Read ↗

A paternal bias in germline mutation is widespread in amniotes and can arise independently of cell divisionsSemantic proximity Read ↗

Paternal age, de novo mutations, and offspring health? New directions for an ageing problem.Semantic proximity Read ↗

A paternal bias in germline mutation is widespread in amniotes and can arise independently of cell division numbers.Semantic proximity Read ↗

How important is DNA replication for mutagenesis?Semantic proximity Read ↗

Male germline vulnerability to DNA damage causes sex-biased mutationSemantic proximity Read ↗

Oxidative stress as a life-history constraint: the role of reactive oxygen species in shaping phenotypes from conception to deathSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.