Article
Biomarkers in tissue from patients with upper gastrointestinal cancers treated with erlotinib and bevacizumab.
Cancer biology & therapy - 15 Apr 2011
Rohrberg Kristoffer Staal, Pappot Helle, Lassen Ulrik, Westman Maj, Olesen René K, Pfeiffer Per, Ladekarl Morten, Sørensen Morten, Christensen Ib J, Skov Birgit G
Abstract excerpt
Malignancies in the upper gastrointestinal (UGI) tract are amongst the most aggressive cancers and only few treatment options exist. We have recently analysed data from a phase II trial where patients with UGI cancers were treated with erlotinib and bevacizumab. The combination therapy could not be recommended in an unselected population of patients with chemo-refractory UGI cancer. However, a subpopulation of...
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